Why Arm-Pit Sweat Smells Bad ???? Know Here ….

Scientists have unravelled the mysterious mechanism behind the armpit’s ability to produce the pungent smell of body odour.

Researchers at the University of York traced the source of underarm odour to a particular enzyme in a certain microbe that lives in the human armpit.

To prove the enzyme was the chemical culprit, the scientists transferred it to an innocent member of the underarm microbe community and noted – to their delight – that it too began to emanate bad smells.

The work paves the way for more effective deodorants and antiperspirants, the scientists believe, and suggests that humans may have inherited the mephitic microbes from our ancient primate ancestors.

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Intraventricular Methotrexate May Improve Survival in Medulloblastoma Subtypes

Adding intraventricular methotrexate to systemic chemotherapy produced favorable survival outcomes in patients with desmoplastic medulloblastoma (DMB) and medulloblastoma with extensive nodularity (MBEN), according to research published in the Journal of Clinical Oncology.

Investigators conducted a prospective trial of 87 children diagnosed with nonmetastatic medulloblastoma before the age of 4 years who were treated from 2001-2011.

At 5 years after diagnosis, the 42 DMB/MBEN patients had a 93% progression-free survival (PFS) rate, a 100% overall survival (OS) rate, and a 93% craniospinal irradiation (CSI)–free survival rate.

“Our results suggest that … poor outcomes of patients treated with systemic chemotherapy alone can be improved by the addition of intraventricular [methotrexate],” wrote Martin Mynarek, MD, of the University Medical Center Hamburg-Eppendorf (Germany), and colleagues.

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