Many patients with knee osteoarthritis who undergo high tibial osteotomy may not require a total knee replacement for at least a decade, a Canadian study suggests.
Researchers examined data on 556 adults who underwent a total of 643 high tibial osteotomy (HTO) procedures from 2002 to 2014 at a large academic teaching hospital in Ontario. Among these patients, the cumulative incidence of total knee replacement was 5% at 5 years and 21% at 10 years, researchers report in CMAJ.
Patients were most likely to require total knee replacement during follow-up when they had greater radiographic severity of knee osteoarthritis prior to HTO (adjusted hazard ratio 1.96). The chance of needing total knee replacement also increased with each additional 10 years of age (aHR 1.50), and each 5-point increase in BMI (aHR 1.31).
“This study suggests the vast majority of patients do not go on to get a total knee replacement within 10 years of undergoing HTO,” said lead study author Codie Primeau of the School of Physical Therapy and Bone and Joint Institute at the University of Western Ontario, in Canada.