Drug-Free Interventions to Reduce Pain or Opioid Consumption After Total Knee Arthroplasty
Evaluation of Comprehensive Skin Toxicity Program for Patients Treated With EGFR Inhibitors
Spinal Metastases
Research Suggests Mammography Screening Performance Metrics Be Based on Final Assessment
Research published in Cancer indicated that conventional mammography screening performance metrics underestimate the interval cancer rate of a mammography screening episode, especially in women with dense breasts or an elevated risk of breast cancer.
Given these findings, the investigators suggested that women, clinicians, policymakers, and researchers consider screening outcome measures based on the final assessment to support informed decisions about routine screening and the need for supplemental breast cancer screening.
“These differences have consequences for women, health care providers, and policymakers considering primary and supplemental breast cancer screening strategies,” the authors wrote.
Using data from 2,512,577 screening episodes among 791,347 individual women taken from 2005 to 2017 across 146 facilities in the US participating in the Breast Cancer Surveillance Consortium, researchers compared screening performance metrics based on the final assessment of screening episode with conventional metrics defined with the initial assessment.
Cutaneous Clues Linked to COVID-19 Coagulation Risk
Skin eruptions could help physicians identify people with severe COVID-19 who are more likely to develop coagulopathies, new evidence suggests.
Researchers at Weill Cornell Medicine NewYork-Presbyterian Medical Center in New York City linked livedoid and purpuric skin eruptions to a greater likelihood for occlusive vascular disease associated with SARS-CoV-2 infection in a small case series.
These skin signs could augment coagulation assays in this patient population. “Physicians should consider a hematology consult for potential anticoagulation in patients with these skin presentations and severe COVID-19,” senior author Joanna Harp, MD, told Medscape Medical News.
“Physicians should also consider D-dimer, fibrinogen, coagulation studies, and a skin biopsy given that there are other diagnoses on the differential as well.”