COVID-19 : Should Healthcare Workers Wear Masks at Home?

Wearing a mask at home, even when everyone is feeling fine, might reduce the risk of frontline healthcare workers transmitting SARS-CoV-2 infection to their families, a recent study from China suggests. But the benefits might not outweigh the costs, according to several physicians interviewed.

“My gut reaction is that home mask use for healthcare workers would place an inordinately high burden on those healthcare workers and their families,” said Jeanne Noble, MD, an emergency care physician at the University of California, San Francisco. “Wearing a mask for a 10-hour shift already represents significant physical discomfort, causing sores across the nose and behind the ears. The emotional toll of the physical distance that comes with mask use, with limited facial expression, is also quite real.”

The suggested benefit of home mask use comes from research published online May 28 in BMJ Global Health. To assess predictors of household transmission of SARS-CoV-2 infection, Yu Wang, MD, of the Beijing Center for Disease Prevention and Control, and colleagues conducted a retrospective study of 124 families in Beijing in which there was a confirmed case of COVID-19 as of February 21. The researchers surveyed family members by telephone about household hygiene and behaviors during the pandemic to examine risk factors for transmission.

Continue reading

Lifestyle Choices Can Reduce Breast Cancer Risk Regardless of Genetics

A “favorable” lifestyle was associated with a reduced risk of breast cancer even among women at high genetic risk for the disease in a study of more than 90,000 women, researchers reported.

The findings suggest that, regardless of genetic risk, women may be able to reduce their risk of developing breast cancer by getting adequate levels of exercise; maintaining a healthy weight; and limiting or eliminating use of alcohol, oral contraceptives, and hormone replacement therapy.

Kawthar Al Ajmi, MSc, of the University of Manchester (England), and colleagues published these findings in JAMA Network Open.

With almost a quarter of breast cancers thought to be preventable in the United Kingdom, “it is important to understand the contribution of modifiable risk factors … and how they affect or add to the inherited genetic factors,” the researchers wrote.

Continue reading

Novel Artificial Heart Valve Could Be Better Than Current Options

A novel polymeric heart valve with potentially greater benefits than current artificial valves has been developed by UK scientists.

The latest animal model and laboratory results of the valve, which could be tested in patients within five years, have been published in  Biomaterials Science.

Researchers developed and tested at International Organisation for Standardisation (ISO) standards a novel prosthetic heart valve (PoliValve) manufactured by injection moulding.

The unique feature of this polymeric valve is that it is made of a self-assembling polymer with a microstructure conferring mechanical anisotropy analogous to that of natural valve tissue.

Continue reading

COVID-19 : Risk of Post-surgery Complications

A UK-led global study shows COVID-19 patients who undergo surgery are at increased risk of postoperative death and pulmonary complications. 

Mortality rates for coronavirus patients after surgery approached those of the most seriously ill patients admitted to intensive care after contracting the virus in the community.

Global Study

Experts at the University of Birmingham-led National Institute for Health Research (NIHR) Global Health Research Unit on Global Surgery published their findings in The Lancet. The study was an international, multicentre, cohort study at 235 hospitals in 24 countries, and included 1128 patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery.

The study showed that pulmonary complications occurred in 577 (51·2%) patients, in whom the 30-day mortality was 38·0% (219 of 577), which accounted for 81·7% (219 of 268) of all deaths. Independent risk factors for mortality included male sex, age 70 years or older, American Society of Anesthesiologists (ASA) physical status classification grades 3–5, surgery for malignant disease, emergency surgery, and major surgery. Overall 30-day mortality was 23·8% (268 of 1128 patients).

Continue reading