Nonalcoholic fatty liver disease (NAFLD) in combination with low thyroid function is associated with an increased risk of all-cause and cardiovascular mortality, according to new research.
For the study, in The American Journal of Gastroenterology, Dr. Donghee Kim of Stanford University School of Medicine, in California, and colleagues examined data from the National Health and Nutrition Examination Survey (NHANES) III, which was conducted from 1988 to 1994.
In particular, they analyzed NHANES III-linked mortality data through 2015 on more than 10,000 participants. There were a total of 2,978 deaths, most commonly due to cardiovascular causes and cancer, during the median follow-up period of 23 years.
The prevalence of NAFLD, defined as ultrasonographically diagnosed hepatic steatosis without coexisting liver disease, was 33.9%, including 19.7% with moderate to severe steatosis.